Figure 2.

APTT for each ratio of test sample to NPP in the mixtures in APTT mixing tests. In this mixing test study, APTT was measured in neat test sample, NPP, and the mixture of the 2. The mix ratio was 1:4, 1:1, and 4:1. The measured APTT was plotted graphically on the Y-axis, and the mix ratio of test sample in the mixture along the X-axis, according to the anti-PS/PT concentration of 0 (A), 25 (B), 37.5 (C), and 50 μg/mL (D). The dashed lines represented the upper limit of NRI in the APTT reagent used, established in our laboratory. anti-PS/PT, antibody against phosphatidylserine/prothrombin complex; APTT, activated partial thromboplastin time; FVIII:C, coagulation factor VIII activity; NPP, normal pooled plasma; NRI, normal reference interval.