Table 2.

Meta-regression to find the association between dementia incidence/prevalence and country-specific factors in 2006 and 2016

	Incidence		Prevalence
2016 Country-level factors	β (95% Cl)	p	β (95% Cl)	p
Female	1.05 (–2.37, 4.46)	0.55	1.56 (–2.14, 5.27)	0.41
Life expectancy at age 65	–0.37 (–0.52, –0.22)	<0.001	–0.14 (–0.26, –0.02)	0.02
Gender difference in life expectancy*	0.12 (–0.06, 0.29)	0.18	0.08 (–0.07, 0.23)	0.32
Education (y)	0.02 (–0.07, 0.12)	0.62	–0.00 (–0.09, 0.09)	0.99
Gender difference in education*	–0.13 (–0.26, –0.00)	0.05	–0.14 (–0.26, –0.02)	0.02
Age group
60–64	Ref		Ref
65–69	0.90 (0.47, 1.33)	<0.001	0.72 (0.35, 1.09)	<0.001
70–74	1.73 (1.30, 2.16)	<0.001	1.43 (1.06, 1.79)	<0.001
75–79	2.61 (2.19, 3.02)	<0.001	2.15 (1.79, 2.51)	<0.001
80–84	3.22 (2.81, 3.64)	<0.001	2.91 (2.54, 3.28)	<0.001
85–89	3.73 (3.29, 4.18)	<0.001	3.56 (3.17, 3.94)	<0.001
90+	4.28 (3.84, 4.73)	<0.001	4.23 (3.85, 4.61)	<0.001
	Incidence		Prevalence
2006 Country-level factors	β (95% Cl)	p	β (95% Cl)	p
Female	3.17 (–1.16, 7.50)	0.15	1.05 (–1.40, 3.50)	0.40
Life expectancy at age 65	–0.20 (–0.40, –0.00)	0.05	–0.18 (–0.30, –0.06)	0.003
Gender difference in life expectancy*	–0.10 (–0.32, 0.13)	0.40	–0.02 (–0.16, 0.13)	0.81
Education (y)	–0.10 (–0.18, –0.02)	0.02	–0.03 (–0.09, 0.03)	0.33
Gender difference in education*	–0.03 (–0.15, 0.08)	0.55	0.02 (–0.07, 0.10)	0.66
Age group
60–64	Ref
65–69	0.83 (0.37, 1.28)	<0.001	0.83 (0.48, 1.18)	<0.001
70–74	1.65 (1.20, 2.11)	<0.001	1.53 (1.18, 1.87)	<0.001
75–79	2.57 (2.13, 3.01)	<0.001	2.25 (1.91, 2.59)	<0.001
80–84	3.19 (2.75, 3.63)	<0.001	3.04 (2.69, 3.39)	<0.001
85–89	3.73 (3.26, 4.20)	<0.001	3.75 (3.38, 4.11)	<0.001
90+	4.34 (3.87, 4.81)	<0.001	4.42 (4.06, 4.79)	<0.001

*‘Gender difference in life expectancy at age 65’ refers to the interaction term gender*life expectancy at age 65, and ‘gender difference in education’ refers to the interaction term gender*education, with male as the reference.