Table 3.

PD-L1 n human tumor cells and intratumoral CD8 positive (CD8${}^{+}$) cells

	PD-L1 IHC in tumor cells	$n$	CD8$+$ cell density (mean $\pm$ SD)	$P$ values
All cancers	Negative	5,016	254.2 $\pm$ 7.1	0.0001
	Positive	484	612.2 $\pm$ 22.9
Mesothelioma, epitheloid	Negative	29	261.6 $\pm$ 54.3	0.0864
	Positive	4	537.9 $\pm$ 146.3
Mesothelioma, other types	Negative	18	231.8 $\pm$ 82.4	0.1312
	Positive	10	446.7 $\pm$ 110.5
Endometrioid carcinoma of the ovary	Negative	28	124.0 $\pm$ 62.6	0.9657
	Positive	5	117.0 $\pm$ 148.2
Serous carcinoma of the ovary	Negative	279	142.0 $\pm$ 24.5	0.0001
	Positive	43	532.1 $\pm$ 62.4
Clear cell carcinoma of the ovary	Negative	7	18.2 $\pm$ 7.7	0.7127
	Positive	2	11.9 $\pm$ 14.5
Carcinosarcoma of the ovary	Negative	20	117.0 $\pm$ 46.6	0.5896
	Positive	4	54.5 $\pm$ 104.2
Invasive breast carcinoma of no special type	Negative	997	294.6 $\pm$ 14.0	0.0001
	Positive	58	699.0 $\pm$ 58.0
Lobular carcinoma of the breast	Negative	134	199.7 $\pm$ 22.3	0.7999
	Positive	1	134.0 $\pm$ 258.0
Medullary carcinoma of the breast	Negative	6	1470.0 $\pm$ 485.9	0.1396
	Positive	3	2872.1 $\pm$ 687.2
Adenocarcinoma of the colon	Negative	1229	259.3 $\pm$ 13.7	0.0001
	Positive	52	692.9 $\pm$ 66.8
Clear cell renal cell carcinoma	Negative	568	435.6 $\pm$ 29.5	0.0001
	Positive	31	1164.2 $\pm$ 126.2
Papillary cell renal cell carcinoma	Negative	127	233.9 $\pm$ 39.7	0.2765
	Positive	27	337.3 $\pm$ 86.0
Oncocytoma	Negative	57	74.0 $\pm$ 18.1	0.3923
	Positive	31	100.2 $\pm$ 24.5
Gastric adenocarcinoma, diffuse type	Negative	69	260.3 $\pm$ 50.5	0.7595
	Positive	2	352.8 $\pm$ 296.5
Gastric adenocarcinoma, intestinal type	Negative	61	324.7 $\pm$ 62.3	0.0001
	Positive	15	1142.5 $\pm$ 125.7
Gastric adenocarcinoma, mixed type	Negative	45	386.4 $\pm$ 94.7	0.1399
	Positive	8	751.9 $\pm$ 224.6
Ductal carcinoma of the pancreas	Negative	351	222.2 $\pm$ 15.8	0.1014
	Positive	42	301.3 $\pm$ 45.5
Pancreatic/Ampullary adenocarcinoma	Negative	34	268.8 $\pm$ 81.1	0.1313
	Positive	4	654.7 $\pm$ 236.4
Sarcomatoid urothelial carcinoma	Negative	7	229.3 $\pm$ 342.1	0.2457
	Positive	17	714.1 $\pm$ 219.5
Granular cell tumor	Negative	19	61.9 $\pm$ 11.1	0.0681
	Positive	1	158.0 $\pm$ 48.3
Leiomyosarcoma	Negative	32	82.7 $\pm$ 28.6	0.1047
	Positive	3	245.5 $\pm$ 93.3