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. 2023 Feb 28;11:20503121231157209. doi: 10.1177/20503121231157209

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© The Author(s) 2023

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — The TFEB (a) gene transcript, the numbers indicate exons, the two noncoding exons and the eight coding exons. In addition, the start codon AUG at exon 3 and the stop codon UGA at exon 10 are shown; (b) the protein is shown schematically, together with the pertinent domains (AD), bHLH region, LZ, and proline-rich domain (Pro-rich), regions, and amino acid residues that are undergoing posttranslational modifications. The numbers show the amino acid location in TFEB.

AD, activation domain; bHLH, basic helix–loop–helix; CARM1, co-activator-associated arginine methyltransferase 1; LZ, leucine zipper; NLS, nuclear localization signal; SUMO, small ubiquitin-like modifier; TFEB, transcription factor EB.