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. 2022 Nov 8;150:e204. doi: 10.1017/S0950268822001182

Table 2.

Baseline characteristics of the study population

N = 3 858 335
Number of individuals included in each study year (n)
2016 3 529 035
2017 3 406 005
2018 3 336 317
2019 3 248 735
Age (years) at study entry
Mean (Minimum, maximum) 47 (16–108)
Age group (years) at study entry (n, %)
16–49 2 086 526 54.08
50–59 680 237 17.63
60–69 467 343 12.11
≥70 624 229 16.18
Sex (n, %)
Male 1 892 342 49.05
Female 1 965 993 50.95
Presence of at-risk medical condition in the pre-period (n, %)
No history of at-risk or high-risk medical condition 1 539 526 39.90
History of any at-risk medical condition 2 178 167 56.45
Chronic diseases
Diabetes mellitus 486 205 12.60
Chronic pulmonary disease (incl. asthma) 1 039 525 26.94
Chronic heart disease 1 576 945 40.87
Neurological disorders 128 109 3.32
Any high-risk medical condition 728 198 18.87
Cancer 247 337 6.41
Cerebrospinal fluid leak 951 0.02
Chronic renal disease 200 377 5.19
Cochlear implant 5837 0.15
Functional or anatomic asplenia, sickle cell disease/other hemaglobinopathy, congenital or acquired asplenia, splenic dysfunction, splenectomy 17 887 0.46
HIV infection 4008 0.10
Immuno-compromising diseases 113 710 2.95
Organ transplant 20 492 0.53
Chronic liver disease 202 125 5.24
Autoimmune disease 100 505 2.60