Table 3.

Incidence rates of ACP and IPD in the overall study population and in each stratification

	ACP		IPD
	N = 171 175		N = 1053
Overall number of episodes	Rate per 100 000 PY	95% CI	Rate per 100 000 PY	95% CI
Overall	1345.43	1339.06–1351.81	8.25	7.76–8.77
Year
2016	1352.33	1339.86–1364.89	8.01	7.08–9.03
2017	1381.83	1369.06–1394.68	7.57	6.65–8.58
2018	1386.47	1373.52–1399.51	9.52	8.48–10.66
2019	1237.52	1225.13–1250.00	7.76	6.81–8.81
Trend test (P value)a	1.00	–	1.00	–
Age at study entry
16–49	512.89	507.49–518.33	1.69	1.40–2.03
50–59	1027.30	1014.59–1040.14	8.76	7.62–10.01
60–69	1675.53	1655.38–1695.85	14.47	12.65–16.47
≥70	4286.49	4257.77–4315.35	24.77	22.64–27.05
Sex
Male	1442.63	1433.20–1452.11	9.11	8.37–9.89
Female	1252.79	1244.21–1261.42	7.44	6.79–8.13
Presence of medical condition in the pre-period
At-risk	1397.33	1387.32–1407.39	7.35	6.64–8.12
High-risk	3202.23	3179.36–3225.23	22.48	20.61–24.48
None	426.76	421.08–432.51	2.56	2.14–3.04

ACP, all-cause pneumonia; CI, confidence interval; IPD, invasive pneumococcal disease; PY, person-year.

^aMann–Kendall test for trend.