Table 6.

Healthcare cost associated with ACP and IPD in patients with at least one ACP or IPD episode, by risk groups (2016–2019)

	ACP				IPD
	Overall	High-risk	At-risk	Healthy	Overall	High-risk	At-risk	Healthy
Number of patients	146 225	61 547	64 534	20 144	965	486	364	115
Outpatients
Visit rate (rate per 1000 PY, 95% CI)	3795 (3775–3815)	3180 (3152–3209)	4028 (3997–4060)	4976 (4913–5040)	1580 (1404–1772)	1615 (1369–1892)	1465 (1191–1784)	1774 (1273–2407)
Total visit cost, €	6 884 025	2 989 113	3 036 097	858 814	18 946	9406	7764	1776
Visit cost per episode, €, (95% CI)	40 (40–41)	40 (39–41)	41 (40–41)	40 (9–41)	18 (13–23)	18 (13–23)	20 (9–30)	14 (3–25)
Total outpatient cost, including visits and prescriptions, €	9 464 319	3 995 777	4 205 183	1 263 360	31 034	15 886	11 533	3615
Outpatient cost per episode, €, (95% CI)	55 (55–56)	53 (52–54)	56 (56–57)	59 (8–60)	29 (22–37)	30 (19–41)	29 (17–41)	28 (14–42)
Inpatients
Hospital admission (rate per 1000 PY, 95% CI)	2928 (2910–2946)	3701 (3670–3732)	2599 (2574–2625)	1563 (1527–1599)	5156 (4834–5493)	5024 (4583–5497)	5417 (4876–6001)	4933 (4069–5926)
Total hospital cost, €	239 426 680	127 976 977	94 020 761	17 428 941	8 471 725	4 360 150	2 838 932	1 272 643
Hospital cost per episode, €, (95% CI)	1399 (1370–1427)	1706 (1659–1752)	1259 (1218–1301)	811 (747–875)	8045 (7092–8999)	8227 (6848–9606)	7205 (5827–8584)	9865 (6536–13 195)
Total inpatient and outpatient cost (€)	248 891 000	131 972 754	98 225 945	18 692 301	8 502 759	4 376 036	2 850 465	1 276 258
Total cost per episode (€, 95% CI)	1454 (1426–1482)	1759 (1712–1806)	1316 (1275–1357)	870 (805–934)	8075 (7121–9028)	8257 (6878–9635)	7235 (5857–8612)	9893 (6565–13 222)

ACP, all-cause pneumonia; CI, confidence interval; IPD, invasive pneumococcal disease; PY, person-year.