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. 2023 Mar 6;13(3):e12229. doi: 10.1002/clt2.12229

TABLE 3.

Correlations between the levels of LTE4 and EDN in patients with AERD or ATA.

Asthma (n = 136) AERD (n = 47) ATA (n = 89)
Sputum EDN Urine EDN Plasma EDN Sputum EDN Urine EDN Plasma EDN Sputum EDN Urine EDN Plasma EDN
Serum LTE4 p = 0.011 p = 0.160 p = 0.008 p = 0.003 p = 0.368 p = 0.017 p = 0.505 p = 0.576 p = 0.419
r = 0.347 r = 0.226 r = 0.605 r = 0.348
Urine LTE4 p = 0.023 p < 0.001 p < 0.001 p = 0.218 p = 0.013 p = 0.002 p = 0.303 p = 0.039 p = 0.001
r = 0.311 r = 0.362 r = 0.388 r = 0.369 r = 0.445 r = 0.228 r = 0.334

Abbreviations: AERD, aspirin‐exacerbated respiratory disease; ATA, aspirin tolerant asthma; EDN, eosinophil‐derived neurotoxin; LT, leukotriene.