FIG. 6.

Growth parameters of Sox8-deficient mice after birth. (A) Body length of age-matched adult wild-type (+/+) and homozygous (−/−) female (f) and male (m) mice measured from nose to anus (n ≥ 10 for each genotype and sex). (B) X-ray autoradiograms of age-matched adult female mice. (C to F) Absolute weight (C and E) and weight gains (D and F) of wild-type (open symbols) and homozygous Sox8-deficient (filled symbols) littermates (n ≥ 6 for each genotype and sex) were monitored for the first 100 days after birth for both males (C and D) and females (E and F). Data are means ± standard errors of the means; statistically significant differences from wild-type controls were observed in weight measurements from postnatal day 19 onwards (P < 0.05 for males and P < 0.001 for females by Student's t test).