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. 2022 Apr 20;54(1):1004–1013. doi: 10.1080/07853890.2022.2063372

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Measurement of colour differences of atrophy, intestinal metaplasia and map-like redness using the endoscopic images. Each sample area at the atrophic border, intestinal metaplasia and map-like redness was imaged by between white-light imaging (WLI) and narrow-band imaging (NBI) and between WLI and texture and colour enhancement imaging (TXI) with the similar composition. (A) The atrophic border is seen in lesser curvature of gastric body. (B) Two expert endoscopists independently set a sample area of the atrophic mucosa by WLI image and delineated the margin of atrophic border on the WLI image (Arrows). (C) The endoscopist manually annotated three points 3–5 mm inside and outside the atrophic border (Circles). (D) The inside and outside points were similarly annotated on the image of NBI with the similar angle and distance. We set three pairs of sample areas and calculated the colour difference between atrophic and non-atrophic mucosal areas with each image of WLI and NBI. (E) The intestinal metaplasia is seen in antrum on the NBI image. (F) The endoscopist set a sample area of the intestinal metaplasia by NBI image and manually annotated three points inside and outside the intestinal metaplasia (Circles). We set three pairs of sample areas and calculated the colour difference between intestinal metaplasia and non- intestinal metaplasia with each image of WLI and NBI.