Table 2.

Gut microbial taxa associated with subjective memory complaints^a

Taxa (class; order; family; genus)		Binary (2+ versus < 2)			Continuous
	Mean relative abundance, %	ORb (95% CI)	p	FDR adjusted pc	ORb (95% CI)	p	FDR adjusted pc
Bacteroidetes
Bacteroidia; Bacteroidales; [Odoribacteraceae]; Odoribacter (genus)	0.28	1.58 (1.03–2.43)	0.038	0.399	1.18 (1.02–1.36)	0.025	0.262
Firmicutes
Clostridia; Clostridiales; Ruminococcaceae; Faecalibacterium (genus)	7.07	1.50 (1.06–2.11)	0.023	0.399	1.12 (1.00–1.25)	0.053	0.393
Clostridia; Clostridiales; Lachnospiraceae; Anaerostipes (genus)	0.18	1.47 (0.95–2.25)	0.085	0.628	1.15 (1.00–1.32)	0.049	0.393
Clostridia; Clostridiales; Veillonellaceae; Phascolarctobacterium (genus)	0.26	0.69 (0.44–1.10)	0.094	0.712	0.80 (0.68–0.95)	0.014	0.180
Erysipelotrichi; Erysipelotrichales; Erysipelotrichaceae; Holdemania (genus)	0.04	2.09 (1.38–3.17)	0.0007	0.038	1.24 (1.08–1.41)	0.002	0.055
Proteobacteria	4.56	1.27 (0.89–1.83)	0.193	0.998	1.19 (1.06–1.34)	0.004	0.033
Betaproteobacteria (class)	1.43	1.61 (1.10–2.35)	0.016	0.135	1.20 (1.07–1.35)	0.002	0.021
Betaproteobacteria; Burkholderiales (order)	1.43	1.61 (1.10–2.35)	0.016	0.158	1.20 (1.07–1.35)	0.002	0.025
Betaproteobacteria; Burkholderiales; Alcaligenaceae (family)	1.38	1.76 (1.20–2.59)	0.005	0.082	1.25 (1.11–1.40)	0.0003	0.006
Betaproteobacteria; Burkholderiales; Alcaligenaceae; Sutterella (genus)	1.38	1.76 (1.20–2.59)	0.005	0.131	1.25 (1.11–1.40)	0.0003	0.018
Deltaproteobacteria (class)	0.35	2.10 (1.43–3.09)	0.0003	0.005	1.27 (1.13–1.42)	0.0002	0.003
Deltaproteobacteria; Desulfovibrionales (order)	0.35	2.10 (1.43–3.09)	0.0003	0.006	1.27 (1.13–1.42)	0.0002	0.003
Deltaproteobacteria; Desulfovibrionales; Desulfovibrionaceae (family)	0.35	2.10 (1.43–3.09)	0.0003	0.010	1.27 (1.13–1.42)	0.0002	0.006
Deltaproteobacteria; Desulfovibrionales; Desulfovibrionaceae; Bilophila (genus)	0.22	1.59 (1.03–2.43)	0.038	0.399	1.22 (1.07–1.40)	0.005	0.090

^aTaxa associated with either binary or continuous SMCs at the nominal level were shown in the table.

^bAdjusting for age, BMI, and race (White versus other).

^cFDR = 5%.