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. 2023 Feb 20;46(3):75–88. doi: 10.1097/CJI.0000000000000455

TABLE 1.

Motifs of Ig-like domains of SARS-COV-2 virus proteins

Protein Alias Motif Start End
S A WFHAIH 64 69
B KVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEY 129 170
C DCTMYIC 737 743
D MQMAYR 900 905
E YHLMSFPQSAPHG 1047 1059
F HVTYVPAQEKNFTTAPAICHDGKAHFPRE 1064 1092
G THWFVTQRNFYEPQI 1100 1114
H DLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHY 1199 1272
E A AILTALRLCAYCCNIVNVSLVKPSFYVYSRVKNLNSSRVPD 32 72
M A WICLLQFAYANRNRFLYIIKLIFLWLLWPVTLACFVLAAVYRINWITGGIAIAMACLV 31 88
B MWSFNPE 109 115
C HHLGRCDIKDLPKEITVATSRTLSYYKLGASQRVAGDSGFAAYSRYRIGNYKLNTDHSSSSDNIA 154 218
N A QGLPNNTASWFTALTQHGKED 43 63
B DQIGYYRRATRRIRGGDGKMKDLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIG 82 147
C LIRQGTDYKHWPQIAQFAPSASAFFGMSRIGMEVTPSGTW 291 330
D FKDQVILLNKHIDAYKTFPPTE 346 367
ORF3a A MDLFMR 1 6
B ASKIITLKKRWQ 59 70
C YLYALVYFLQSINFVRIIMRLWLCWKCRSKNPLLYDANYFLCWHTNCYDYCIPYNS 107 162
D EHDYQIGGYTEKWESGVKDCVVLHSYFTSDYYQ 181 213
E HVTFFIYNKIVDEPEEHVQIHTIDGSSGVVNPVMEPIYD 227 265
ORF6 A MFHLVDFQVTIAEILLIIMRTFKVSIWNLDYIINLIIKNLSKSLTENKYSQLDEEQPMEID 1 61
ORF7a A MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNSPFHPLADNKFALTCFSTQFAFACPDGVKHVYQLRARSVSPKLFIRQEEVQELYSPIFLIVAAIVFITLCFTL 1 116
ORF7b A MIELSLIDFYLCFLAFLLFLVLIMLIIFWFSLELQDHNETCHA 1 43
ORF8 A MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWYIRVGARKSAPLIELCVDEAGSKSPIQYIDIGNYTVSCLPFTINCQEPKLGSLVVRCSFYEDFLEYHDVRV 1 116
ORF10 A MGYINVFAFPFTIYSLLLCRMNSRNYIAQVDVVNFNLT 1 38
nsp2 A IDTKRGVYCCREHEHEIAWYTERSEKSYELQTPF 42 75
B CDHCGETSWQTGDFVKATCE 143 162
nsp3 A SHMYCSFY 100 107
B EDDYQGKPLEFGATSAALQPEEEQEEDW 134 161
C SEYTGNYQCGHYKHITSKE 1007 1025
D HKPIVWH 1169 1175
E HFISNSWLMWLIINLVQM 1539 1556
F YYVWKSYVHVVDGCNSSTCMMCYKRNRATRVE 1573 1604
G SHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPF 1888 1922
nsp4 A MRFRRAFGEYSH 302 313
B FLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV 359 402
nsp6 A YFNMVYMPASWVMRIMTWLDM 80 100
nsp10 A SCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTC 72 103
B CTVCGMWKGYGCSCDQ 117 132
RNA-dependent RNA polymerase A RYFKYWDQTYHPNCVNCLDDRCI 285 307
B FYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIM 594 633
C SRYWEPEFYEAMYTPH 913 928
2′-O-ribose methyltransferase A EHSWNADLYKLMGHFAWWT 173 191
3C-like proteinase A YDCVSFCYMHHMELP 154 168
3′-to-5′ exonuclease A DMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIG 48 88
B PPPGDQFKHLIP 140 151
C TYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 223 300
D RHHANEYRLYLDAYNM 485 500
helicase A MPLSAPTLVPQEHYVRITG 233 251
B SAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYN 468 516

Ig indicates immunoglobulin; SARS-COV-2, severe acute respiratory syndrome coronavirus 2.