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. 2023 Jan 27;7(2):e0029. doi: 10.1097/HC9.0000000000000029

FIGURE 1.

FIGURE 1

Malassezia restricta is one of the fungal species most frequently present in patients with alcohol use disorder (AUD) and its presence is associated with more severe alcohol-associated liver disease. A, Out of 69 tested fungal species, 35 fungal species were present in at least 1 AUD patient. Fungal species depicted in red are present in >50% of AUD patients, whereas species visualized in blue are more variably present in AUD patients with a positivity of <50% of all AUD patients. B, Serum ALT of M. restricta negative AUD patients (n=36) and M. restricta positive AUD patients (n=30). C, Serum GGT of M. restricta negative AUD patients (n=35) and M. restricta positive AUD patients (n=30). D, Serum CK18-M65 of M. restricta negative AUD patients (n=34) and M. restricta positive AUD patients (n=29). p Values were determined by Mann-Whitney test. A p value of ≤0.05 was considered statistically significant. Abbreviations: ALT, alanine aminotransferase; CK18-M65, caspase-cleaved and intact cytokeratin 18; GGT, gamma-glutamyltransferase.