Table 3.

Age and Scan Quality adjusted Regional Rate of Macula Ganglion Cell Complex Thickness Thinning and Vessel Density Loss in Healthy, OHT and GON Eyes

	A. Healthy	B. OHT	C. GON	P Value# (a, b)
	Mean (95%CI), P Value*	Mean (95%CI), P Value*	Mean (95%CI), P Value*	A vs. B	B vs. C	A vs. C
Ganglion Cell Complex Thickness Thinning Rate (μm/year)
Inferior	−0.28 (−0.67, 0.11), 0.158	−0.09 (−1.08, 0.90), 0.858	−0.65 (−1.42, 0.12), 0.098	0.677, 0.700	0.775, 0.770	0.379, 0.379
Superior	−0.08 (−0.51, 0.34), 0.705	−0.58 (−1.13, −0.03), 0.038	−0.96 (−1.52, −0.40), 0.001	0.083, 0.098	0.995, 0.950	0.088, 0.091
Temporal	−0.01 (−0.37, 0.36), 0.976	−0.64 (−1.35, 0.07), 0.076	−0.68 (−1.28, −0.09), 0.024	0.017, 0.022	0.374, 0.384	0.051, 0.059
Nasal	−0.23 (−0.66, 0.21), 0.306	−0.48 (−1.14, 0.18), 0.154	−0.90 (−1.61, −0.18), 0.014	0.019, 0.023	0.288, 0.296	0.074, 0.083
Vessel density Loss Rate (%/year)
Inferior	−0.75 (−1.26, −0.25), 0.003	−0.45 (−0.87, −0.03), 0.037	−0.65 (−1.05, −0.25), 0.001	0.219, 0.160	0.293, 0.225	0.763, 0.733
Superior	−0.83 (−1.36, −0.30), 0.002	−0.66 (−1.17, −0.16), 0.009	−0.67 (−1.09, −0.25), 0.002	0.346, 0.228	0.771, 0.600	0.437, 0.396
Temporal	−0.68 (−1.01, −0.34), <.0001	−0.78 (−1.22, −0.33), 0.001	−0.85 (−1.24, −0.47), <.0001	0.973, 0.838	0.673, 0.525	0.622, 0.638
Nasal	−0.94 (−1.44, −0.43), <.0001	−0.70 (−1.14, −0.26), 0.002	−0.81 (−1.13, −0.49), <.0001	0.100, 0.100	0.482, 0.496	0.263, 0.235

Abbreviations: OHT, ocular hypertension; GON, glaucomatous optic neuropathy; CI, confidence interval

^*P value represents whether the mean rate is significantly different from zero.

^#P value represents whether the mean rate is significantly different between groups, a, age and QI adjusted; b, age, race, mean IOP, CCT, and QI adjusted.

Values with statistical significance (P≤0.05) or borderline significance (0.05<P<0.1) are shown in bold.