Figure 5.

Case Report 2

(A) Fetal echocardiogram at 25 weeks in a child with hydrops fetalis demonstrated severely depressed biventricular systolic dysfunction with excessive trabeculation (Video 3). (B) Supraventricular tachycardia in this fetus developed 1 week later. Forty-eight hours after delivery, left ventricular EF reduced to 33% (Video 4). (C) Five years later, the same patient demonstrated progressive left ventricular dilatation with an left ventricular end-diastolic diameter Z score of +2.7 and borderline EF of 50% and global longitudinal strain of −17% (Video 5). The working diagnosis was cardiomyopathy with excessive trabeculation. Neonates and children with excessive trabeculation have been understudied, with low rates of longitudinal follow-up. Such patients should routinely undergo follow-up, with close clinical evaluation and potentially neuromuscular disease testing. If familial disease is suspected, genetic testing may be indicated. Abbreviation as in Figure 4.