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. 2023 Mar 7;42(4):112271. doi: 10.1016/j.celrep.2023.112271

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© 2023 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Result of BLI competition mapping of BA.2 mAbs

(A) Competition ratio results (using Mabscape; see STAR Methods). Numbers close to 0 represent complete competition between pairs of antibodies, and numbers close to 1 mean no competition. Cells are colored as red, yellow, and green, with the values ranging from 0 to 1. Antibodies with known structures (Omi-12, Omi-42, EY6A, S309, COVOX-45, COVOX-58, COVOX-278, AZD1061, and AZD8895) were used as references.

(B) RBD surface representation with ACE2-binding site in green and balls corresponding to center of gravity of mapped potent BA.2 mAbs colored according to variable gene usage.

See also Figure S1.