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. 2023 Feb 21;11:1104709. doi: 10.3389/fcell.2023.1104709

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Copyright © 2023 Burkhardt, Bucher, Löffler, Rinne, Duda, Geissler, Schulz and Schmidt-Bleek.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Anatomical locations of human WAT/BAT and beige adipose tissue with details on adipose tissue composition adapted from Lenz, et al. (2020): (A) Phenotype of WAT/BAT and beige adipose tissue differs in mitochondrial density and lipid droplet morphology. (B) Specific locations of each type of fat depot (brown or white) can be found throughout the body. Highlighted are the locations of adipose tissue surrounding organs, muscles and blood vessels. (C) Adipose tissue composition including adipocytes, immune cells, endothelial cells and mesenchymal stromal cells, which are all known to facilitate endocrine functions, energy storage and energy metabolism.