Table 1.
Demographic and clinical data of the study cohort (n = 30).
| Characteristics | No CSF diversion (n = 23) | CSF diversion (n = 7) | P-value | ||
|---|---|---|---|---|---|
| Neonatal characteristics | |||||
| Gestational age at birth (weeks, SD) | 26.61 ± 1.06, SD = 2.59 | 26.57 ± 2.30, SD = 3.10 | 0.978 | ||
| Birth weight (g) | 976.1 ± 125.2, SD = 306.4 | 1,088.7 ± 392.2, SD = 529.43 | 0608 | ||
| Head circumference at birth (cm) | 24.8 ± 1.09, SD = 2.7 | 26.9 ± 6.3, SD = 8.47 | 0.529 | ||
| Male sex (%) | 10 (43.5) | 4 (57.1) | 0.109 | ||
| Apgar at 5 min | 6.09 ± 0.99, SD = 2.4 | 7 ± 1.54, SD = 2.1 | 0.349 | ||
| Inborn (%) | 21 (91.3) | 3 (42.9) | 0.0002 | ||
| Cesarean section delivery (%) | 9 (39.1) | 2 (28.6) | 0.035 | ||
| Maternal characteristics | |||||
| Antenatal corticosteroids (complete course) % | 11 (47.8) | 1 (14.3) | 0.004 | ||
| Maternal age (years) | 31.48 ± 2.65, SD = 6.5 | 29.57 ± 4.9, SD = 6.6 | 0.519 | ||
| Neonatal complications | |||||
| Invasive ventilation > 1 week (%) | 15 (65.2) | 5 (71.4) | 0.025 | ||
| hsPDA (%) | 12 (52.2) | 5 (71.4) | 0.090 | ||
| GMH-IVH grade42 | Grade I: 7 (30.4) | Grade I: 0 (0.0) | 0.015 | ||
| Grade II: 10 (43.5) | Grade II: 2 (28.6) | ||||
| Grade III: 4 (17.4) | Grade III: 2 (28.6) | ||||
| Grade IV: 2 (8.7) | Grade IV: 3 (42.9) | ||||
| Culture-positive or clinical sepsis (%) | 19 (82.6) | 6 (85.7) | 0.009 | ||
| Hypotension, inotrope use (%) | 6 (26.1) | 4 (57.1) | 0.527 | ||
| BPD (%) | 8 (34.8) | 4 (57.1) | 0.248 | ||
| PVL (%) | 7 (30.4) | 5 (71.4) | 0.564 | ||
| VP shunt (%) | 0 (0.0) | 3 (42.9) | – | ||
| Death before discharge (%) | 0 (0.0) | 1 (4.3) | – | ||
| Number of sessions (Mean, median) | 3.7, 3 | 9.6, 11 | – | ||
RDS Respiratory Distress Syndrome, hsPDA hemodynamically significant Patent Ductus Arteriosus, PVL periventricular leukomalacia, VP shunt ventriculoperitoneal shunt, Session time of 3DcUS and fNIRS acquisition.