Table 1.
Basic characteristics of the study population in NHANES 2007-2018 (n = 22220).
| Characteristics | Overall | SII (109/L) | P value | |
|---|---|---|---|---|
| < 330 | ≥ 330 | |||
| Number | 22220 | 5722 | 16498 | |
| Age | 49.45 ± 17.36 | 49.25 ± 17.24 | 49.52 ± 17.40 | <0.001 |
| Family income-to-poverty ratio | 2.59 ± 1.64 | 2.58 ± 1.63 | 2.59 ± 1.64 | 0.363 |
| BMI (kg/m2) | 29.34 ± 7.04 | 28.47 ± 6.35 | 29.64 ± 7.25 | <0.001 |
| Gender | <0.001 | |||
| Male | 11755 (52.90%) | 2414 (42.19%) | 8051 (48.80%) | |
| Female | 10465 (47.10%) | 3308 (57.81%) | 8447 (51.20%) | |
| Race/Ethnicity | <0.001 | |||
| Non-Hispanic Black | 4510 (20.30%) | 1833 (32.03%) | 2677 (16.23%) | |
| Non-Hispanic White | 10171 (45.77%) | 2000 (34.95%) | 8171 (49.53%) | |
| Hispanic/Mexican | 5276 (23.74%) | 1234 (21.57%) | 4042 (24.50%) | |
| Other Races | 2263 (10.18%) | 655 (11.45%) | 1608 (9.75%) | |
| Education level | 0.408 | |||
| ≤ High school | 4752 (21.39%) | 1239 (21.65%) | 3513 (21.29%) | |
| > High school | 17468 (78.61%) | 4483 (78.35%) | 12985 (78.71%) | |
| Smoking history | 0.010 | |||
| Non-smoker | 11093 (49.92%) | 3004 (52.50%) | 8089 (49.03%) | |
| Smoker | 11127 (50.08%) | 2718 (47.50%) | 8409 (50.97%) | |
| Alcohol drinking history (drinks/week) | 0.156 | |||
| < 1 | 14262 (64.19%) | 3633 (63.49%) | 10629 (64.43%) | |
| 1-3 | 5645 (25.41%) | 1500 (26.21%) | 4145 (25.12%) | |
| ≥ 4 | 2313 (10.41%) | 589 (10.29%) | 1724 (10.45%) | |
| Diabetes mellitus | <0.001 | |||
| No | 18067 (81.31%) | 4709 (82.30%) | 13358 (80.97%) | |
| Yes | 4153 (18.69%) | 1013 (17.70%) | 3140 (19.03%) | |
| Coronary heart disease | 0.090 | |||
| No | 21278 (95.76%) | 5472 (95.63%) | 15806 (95.81%) | |
| Yes | 942 (4.24%) | 250 (4.37%) | 692 (4.19%) | |
| Kidney stone | 0.010 | |||
| No | 20026 (90.13%) | 5245 (91.66%) | 14781 (89.59%) | |
| Yes | 2194 (9.87%) | 477 (8.34%) | 1717 (10.41%) | |
Data were n (%) or mean ± SD; BMI, body mass index; SII, systemic immune-inflammatory index.