Table 6.
Sensitivity Analyses
| Model | Goodness of Fit | Overall VT, %, HIV Negative | Overall VT, %, HIV Positive | Transmission by Stage, % | |
|---|---|---|---|---|---|
| Preferred model | |||||
| ȃConstrained interaction | 741.6 | 7.2 | 12.1 | 24.8 | 9.3 |
| Statistical uncertainty in preferred model | |||||
| ȃLower (2.5%) credible limit | … | 5.6 | 8.6 | 12.1 | 0.5 |
| ȃUpper (97.5%) credible limit | … | 8.9 | 16.8 | 40.8 | 30.6 |
| Model choice | |||||
| ȃMain effect model | 742.4 | 7.2 | 11.8 | 24.6 | 9.3 |
| ȃSimple interaction model | 743.0 | 7.2 | 11.8 | 24.6 | 9.2 |
| Proportion low HCV viral load and proportion RNA negative | |||||
| ȃBoth odds lower by a factor of 1.6 | 742.2 | 7.4 | 12.2 | 24.6 | 9.1 |
| ȃBoth odds higher by a factor of 1.6 | 740.9 | 7.0 | 12.1 | 24.8 | 9.4 |
Comparison of preferred model and alternatives. The preferred model is constrained interaction and assumes that 68.9% of the HIV negative and 90.7% of the HIV positive with unknown HCV RNA status are RNA positive. Goodness of fit is posterior mean deviance.
Abbreviations: HCV, hepatitis C virus; HIV, human immunodeficiency virus; VT, vertical transmission.