Table.
Upregulated Proteins Identified by Liquid Chromatography–Tandem Mass Spectrometry in Human Dental Pulp Stem Cells Incubated with Protein S100 Family-Derived Peptide or S100A8 for NF-κB Signaling and MAPK Signaling.
| Identified Cell Membrane–Derived Protein | Quantitative value (a.u.) | Associated Signaling Pathway | ||
|---|---|---|---|---|
| Peptide No. 1 | S100A8 | Control | ||
| Cell membrane proteins | ||||
| Flotillin 1 (FLOT1) | 10.104 | 6.3733 | 4.3079 | NF-κB signaling |
| Very long-chain (3R)–3-hydroxyacyl-CoA dehydratase (3KCR1) | 6.7361 | 5.3111 | 3.231 | |
| Protein LYRIC (LYRIC) | 5.6134 | 3.1867 | 2.154 | |
| Gap junction α1 protein (GJA1) | 3.3681 | 4.2489 | 1.077 | |
| Dual specificity mitogen-activated protein kinase kinase 1 (MAP2K1) | 0 | 2.1244 | 2.154 | MAPK signaling |
| Cadherin 2 (CDH2) | 0 | 3.1867 | 3.231 | |
| GTPase Nras (NRAS) | 0 | 7.4355 | 7.5389 | |
| Mitogen-activated protein kinase 1 | 1.1227 | 2.1244 | 3.231 | |
| Cytoplasmic proteins | ||||
| Protein S100A13 (S100A13) | 1.889 | 1.8042 | 0.93281 | NF-κB signaling |
| Nucleolar protein 3 (NOL3) | 1.889 | 1.8042 | 0.93281 | |
| Adapter molecule crk (CRK) | 2.8335 | 6.3146 | 6.5297 | MAPK signaling |
| Proteasome subunit β type 7 | 0 | 2.7062 | 3.7312 | |
MAPK, mitogen-activated protein kinase; NF-κB, nuclear factor–κB.