Table 3.
In vitro antioxidant activity of crude and synthetic derivatives using different concentrations of the compounds (50, 75, and 100 µg/mL)
| Compound | Concentration (µg/mL) | |||
|---|---|---|---|---|
| 50 | 75 | 100 | IC50 | |
| Metronidazole | ns | ns | ns | ns |
| 10a | 37.12±0.70 | 38.21±0.54 | 38.10±1.72 | 70.42±0.15 |
| 10b | 39.14±0.22 | 40.57±0.32 | 42.71±0.25 | 70.52±0.54 |
| 10c | 65.21±0.26 | 66.30±0.35 | 67.21±0.29 | 85.21±0.85 |
| 10d | 55.10±0.42 | 56.24±0.37 | 27.31±0.35 | 80.10±0.46 |
| 10e | 60.21±1.45 | 62.30±0.20 | 65.20±0.15 | 82.52±0.13 |
| 10f | 61.70±0.31 | 67.76±0.29 | 71.98±0.17 | 70.45±0.12 |
| Ascorbic acid | 78.01±0.75 | 81.01±0.85 | 84.21±0.41 | 60.10±0.82 |
| Blank | ns | ns | ns | ns |
ns: No scavenging activity; Data are drived from triplicate tests and expressed as mean±SD.