Table 1.
The prognostic significance of S100A4 mRNA levels for disease-free survival in patients with CRC revealed by univariate and multivariate COX analysis.
| Parameter | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Disease-free survival | ||||||
| Age <70 years>70 years | 1,100 | 0,682-1,796 | 0,678 | 1,140 | 0,598-2,197 | 0,680 |
| Stage Early (1-2) Advanced (3) | 2,100 | 1,293-3,416 | 0,002 | 3,760 | 0,409-34,586 | 0,240 |
| Tumor size T1-2 T3-4 | 2,220 | 1,102-4,502 | 0,020 | 1,360 | 0,588-3,162 | 0,469 |
| Vascular invasion Negative Positive | 1,470 | 0,825-2,622 | 0,190 | 1,040 | 0,508-2,168 | 0,895 |
| Lymphovascular invasion Negative Positive | 1,650 | 0,997-2,732 | 0,050 | 1,630 | 0,802-3,336 | 0,175 |
| Lymphatic metastasis Negative Positive | 2,220 | 1,382-3,595 | 0,001 | 6,440 | 0,747-55,591 | 0,090 |
| S100A4 expression <10,75>10,75 | 2,740 | 1,604-4,689 | 0,0002 | 3,730 | 1,917-7,274 | 0,0001 |