Table 2.
The prognostic significance of S100A4 mRNA levels for disease-free survival with colon cancer revealed by univariate and multivariate COX analysis.
| Parameter | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Disease-free survival | ||||||
| Age <70 years>70 years | 1,300 | 0,754-2,241 | 0,344 | 1,267 | 0,607-1,439 | 0,527 |
| Stage Early (1-2) Advanced (3) | 1,820 | 1,040-3,185 | 0,035 | 0,393 | 0,038-4,047 | 0,433 |
| Tumor size T1-2 T3-4 | 2,190 | 0,895-4,867 | 0,054 | 1,762 | 0,654-4,749 | 0,262 |
| Vascular invasion Negative Positive | 1,680 | 0,896-3,151 | 0,105 | 1,195 | 0,506-2,821 | 0,684 |
| Lymphovascular invasion Negative Positive | 1,790 | 1,000-3,206 | 0,049 | 1,609 | 0,673-3,843 | 0,284 |
| Lymphatic metastasis Negative Positive | 1,990 | 1,154-3,441 | 0,013 | 3,850 | 0,424-34,939 | 0,230 |
| S100A4 expression <10,75 >10,75 | 4,730 | 2,332-9,626 | <0,0001 | 10,526 | 3,655-30,310 | <0,0001 |