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. 2022 Mar 1;191(8):1485–1495. doi: 10.1093/aje/kwac035

Table 4.

Example of Upwards Bias Due to Nondifferential, Dependent Exposure Misclassification

Outcome Status (n)
Exposure Status D+ D Total (n) Risk a RR
Correctly classified data
 Exposed 20 180 200 0.10 1.00
 Unexposed 60 540 600 0.10 1.00b
Exposure and outcome misclassified with 1% dependent errors
 Exposed 25 180 205 0.12 1.22
 Unexposed 60 535 595 0.10 1.00b

Abbreviation: RR, risk ratio.

a Risk = number in D+/total number.

b Referent.