Table 1. Case descriptions and planning parameters of 10-fraction stereotactic radiosurgery.
Primary: primary organ; Int.: The interval between the acquisition of magnetic resonance images for planning and the initiation of stereotactic radiosurgery; GTV: gross tumor volume; Max.: maximum; PTV: planning target volume; TTP: time to tumor progression; BED10: biological effective dose based on the linear-quadratic model with an alpha/beta ratio of 10; % isodose: reference isodose normalized to 100% at the isocenter; SCC: squamous cell carcinoma; LCC: large cell carcinoma; Adeno: adenocarcinoma; IDC: invasive ductal carcinoma
Absolute doses of 66.3 Gy, 53 Gy, 42 Gy, and 37 Gy in 10 fractions correspond approximately to 110.3 Gy, 81.1 Gy, 59.6 Gy, and 50.7 Gy for BED10 and 28.6 Gy, 23.9 Gy, 19.9 Gy, and 18.1 Gy for absolute dose in single fraction estimated by BED10, respectively.
| Case | Primary | Int. (days) | GTV | GTV Boundary | Isocenter | PTV Boundary | TTP (month) | ||||||
| (Max. diameter) | |||||||||||||
| (Pathology) | |||||||||||||
| Absolute dose | Coverage | BED10 | % isodose | Absolute dose | BED10 | Margin | Absolute dose | Coverage | |||||
| 1 | Esophagus | 4 | 15.3 cm3 | 45.7 Gy | 99% | 66.6 Gy | 87.0% | 52.5 Gy | 80.1 Gy | 2 mm | 39.4 Gy | 98% | 2.5-4.5 |
| (SCC) | |||||||||||||
| (38 mm) | |||||||||||||
| 2 | Lung | 6 | 10.9 cm3 | 49.0 Gy | 99% | 73.0 Gy | 81.7% | 60.0 Gy | 96.0 Gy | 2 mm | 34.8 Gy | 98% | 2.5 |
| (LCC) | |||||||||||||
| (33 mm) | |||||||||||||
| 3 | Lung | 6 | 19.1 cm3 | 53.0 Gy | 97% | 81.1 Gy | 80.0% | 66.3 Gy | 110.3 Gy | 2 mm | 37.0 Gy | 98% | (18.0-20.7) |
| (Adeno) | |||||||||||||
| (38 mm) | |||||||||||||
| 4 | Breast | 10 | 26.2 cm3 | 55.0 Gy | 100% | 85.3 Gy | 83.0% | 66.3 Gy | 110.3 Gy | (2 mm) | (42.5 Gy) | (98%) | (17.0) |
| (IDC) | |||||||||||||
| (49 mm) | 3 mm | 37.0 Gy | 99% | ||||||||||