Figure 3.

BR101801 has an anti-cancer effect by inducing apoptosis in DLBCL. A. SU-DHL-6 cells were treated with serial concentrations of BR101801 for 24 h, followed by Western blot analysis with the indicated antibodies. B. Active caspase 3/7 probe live imaging. SU-DHL-6 cells and DOHH-2 cells were treated with an active caspase 3/7 probe after treatment with 250 nM BR101801 for 16 h. C. Flow cytometric analysis of Annexin V and PI in SU-DHL-6 cells and DOHH-2 treated with BR101801. D. DLBCL cells were stained with anti-Cytochrome C antibody following treatment with BR101801 for 16 h. Scale bar, 30 μm. Data are presented as the mean ± S.D. (**P < 0.01, ***P < 0.001 vs Con).