Table 2.
Univariate and multivariate analyses of the prognostic factors for overall survival in GC
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| HR | P-value | 95% CI | HR | P-value | 95% CI | |
| POM121 expression | ||||||
| High vs Low or no | 2.020 | <0.001* | 1.619 2.520 | 1.502 | <0.001* | 1.197 1.883 |
| Age (year) | ||||||
| <60 vs ≥60 | 1.319 | <0.001* | 1.073 1.621 | 1.171 | 0.143 | 0.948 1.447 |
| Gender | ||||||
| Male vs Female | 1.024 | 0.831 | 0.825 1.270 | |||
| Differentiation | ||||||
| Well vs Moderate vs Poor | 1.259 | <0.001* | 1.108 1.430 | 1.137 | 0.040* | 1.006 1.287 |
| Tumor disameter | ||||||
| Tis + T1 + T2 vs T3 + T4 | 1.074 | 0.226 | 0.957 1.205 | |||
| Lymph node metastasis | ||||||
| N0 vs N1 + N2 | 0.975 | 0.577 | 0.893 1.065 | |||
| Distant metastasis | ||||||
| M0 vs M1 | 5.253 | <0.001* | 4.164 6.627 | 2.539 | <0.001* | 1.967 3.277 |
| TNM stage | ||||||
| 0 + I + II vs III + IV | 1.477 | <0.001* | 1.376 1.586 | 1.180 | <0.001* | 1.089 1.279 |
| Her-2 | ||||||
| Negative vs Positive | 0.270 | <0.001* | 0.238 0.306 | 0.329 | <0.001* | 0.287 0.377 |
HR: Hazard Ratio; CI: Confidence Interval.
*
P<0.05.