Table 5.
Annual percentage change (APC) in age-adjusted incidence rates (number of breast cancer cases per 100,000 population) in women in 2010-2019 by tumor stage, triple-negative breast cancer status and race/ethnicity
| Race/Ethnicity | Triple-negative breast cancer | Non-Triple-negative breast cancer | Total breast cancer (triple-negative and non-triple-negative breast cancer) | ||||||
|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
|||||||
| N. Cases | Incidence rate (95% CI) | APC (95% CI) from 2010 to 2019 | N. Cases | Incidence rate (95% CI) | APC (95% CI) from 2010 to 2019 | N. Cases | Incidence rate (95% CI) | APC (95% CI) from 2010 to 2019 | |
| Local stage Breast Cancer | |||||||||
| Non-Hispanic white | 11.0 (10.9-11.2) | -0.5 (-2.5-1.5) | 238,689 | 107 (106.6-107.4) | 1.8*** (1.0-2.5) | 262,038 | 118.0 (117.6-118.5) | 1.5*** (0.8-2.3) | |
| Non-Hispanic Asians and Pacific Islanders | 2,893 | 7.5 (7.3-7.8) | 1.1 (-2.4-4.7) | 31,778 | 83.0 (82-83.9) | 2.4*** (1.3-3.5) | 34,671 | 90.5 (89.5-91.5) | 2.3*** (1.2-3.3) |
| Non-Hispanic black | 6,689 | 18.6 (18.1-19.1) | 0.4 (-1.7-2.6) | 27,340 | 77.2 (76.3-78.2) | 2.1*** (0.4-3.8) | 34,029 | 95.8 (94.8-96.9) | 1.7*** (0.3-3.2) |
| American Indians and Alaska Natives | 215 | 8.4 (7.3-9.6) | 0.5 (-10.8-13.3) | 1,909 | 72.4 (69.1-75.8) | 1.9 (-3.4-7.4) | 2,124 | 80.8 (77.3-84.4) | 1.7 (-3.7-7.5) |
| Hispanics | 4,739 | 8.3 (8.1-8.5) | 1 (-3-5.1) | 36,253 | 66.8 (66.1-67.5) | 2.4*** (0.6-4.3) | 40,992 | 75.1 (74.4-75.9) | 2.3*** (0.8-3.8) |
| Sub-Total | 38,016 | 11.0 (10.9-11.1) | -0.2 (-2.1-1.8) | 337,626 | 95.4 (95.1-95.8) | 1.7*** (1.0-2.5) | 375,642 | 106.5 (106.1-106.8) | 1.5*** (0.8-2.3) |
| Regional Stage Breast Cancer | |||||||||
| Non-Hispanic white | 10,616 | 5.2 (5.1-5.4) | -1.8** (-4.3-0.7) | 91,171 | 43.7 (43.4-44.0) | -0.2 (-0.9-0.6) | 101,787 | 48.9 (48.6-49.3) | -0.4 (-1.0-0.2) |
| Non-Hispanic Asians and Pacific Islanders | 1,504 | 4.0 (3.8-4.2) | -0.7 (-6.0-5.0) | 13,706 | 36.2 (35.6-36.8) | 1.7* (-0.5-3.9) | 15,210 | 40.1 (39.5-40.8) | 1.5* (-0.8-3.8) |
| Non-Hispanic black | 4,310 | 12.1 (11.7-12.5) | -0.1 (-3.1-3.0) | 15,763 | 44.4 (43.7-45.1) | 0.4 (-1.2-2.1) | 20,073 | 56.5 (55.7-57.3) | 0.3 (-1.2-1.8) |
| American Indians and Alaska Natives | 119 | 4.9 (4.1-5.9) | -2.1 (-18.9-18) | 944 | 36.2 (33.9-38.7) | 0.0 (-5.9-6.2) | 1,063 | 41.1 (38.6-43.8) | -0.3 (-5.5-5.1) |
| Hispanics | 3,058 | 5.2 (5-5.4) | 0.0 (-2.8-3.0) | 20,575 | 35.9 (35.4-36.4) | 0.3 (-1.6-2.3) | 23,633 | 41.1 (40.6-41.7) | 0.3 (-1.2-1.8) |
| Sub-Total | 19,678 | 5.9 (5.8-5.9) | -1.0* (-2.8-0.8) | 142,801 | 41.8 (41.6-42) | 0.1 (-0.7-1.0) | 162,479 | 47.6 (47.4-47.9) | 0.0 (-0.8-0.8) |
| Distant Stage Breast Cancer | |||||||||
| Non-Hispanic white | 2,458 | 1.1 (1.1-1.2) | 2.0** (-0.8-5) | 17,047 | 7.8 (7.7-7.9) | 1.9** (0.0-3.8) | 19,505 | 8.9 (8.8-9.0) | 1.9*** (0.3-3.5) |
| Non-Hispanic Asians and Pacific Islanders | 277 | 0.7 (0.6-0.8) | 1.7 (-10.7-15.8) | 2,224 | 5.8 (5.6-6.0) | 3.6** (-0.4-7.8) | 2,501 | 6.5 (6.3-6.8) | 3.4*** (0.3-6.7) |
| Non-Hispanic black | 1,004 | 2.8 (2.6-3.0) | 0.8 (-3.2-4.9) | 3,677 | 10.3 (10.0-10.6) | 0.7 (-1.9-3.4) | 4,681 | 13.1 (12.7-13.5) | 0.7 (-1.5-3.1) |
| American Indians and Alaska Natives | 32 | 1.2 (0.8-1.7) | -8.5 (-29.9-19.4) | 179 | 7.0 (5.9-8.1) | 8.1*** (1.5-15.2) | 211 | 8.2 (7.1-9.4) | 5.4 (-3.8-15.4) |
| Hispanics | 593 | 1.1 (1.0-1.2) | 5.4** (0.1-11.0) | 3,205 | 5.7 (5.5-5.9) | 2.1* (-1.1-5.3) | 3,798 | 6.8 (6.0.6-7) | 2.6** (-0.1-5.3) |
| Sub-Total | 4,371 | 1.3 (1.2-1.3) | 2.1 (-1.4-5.7) | 26,421 | 7.6 (7.5-7.6) | 1.8*** (0.4-3.1) | 30,792 | 8.8 (8.7-8.9) | 1.8*** (0.7-2.9) |
| Unknown stage or missing/not coded | |||||||||
| Non-Hispanic white | 272 | 0.1 (0.1-0.1) | 10.0* (-5.3-27.7) | 2,180 | 0.9 (0.9-1.0) | 4.9* (-5.0-15.9) | 2,452 | 1.1 (1.0-1.1) | 5.5* (-4.7-16.8) |
| Non-Hispanic Asians and Pacific Islanders | 53 | 0.1 (0.1-0.2) | 3.3 (-19.2-32.1) | 353 | 0.9 (0.0.8-1.0) | 3.8 (-11.1-21.3) | 406 | 1.1 (1-1.2) | 4.1 (-10.6-21.2) |
| Non-Hispanic black | 99 | 0.3 (0.2-0.3) | 1.9 (-16.6-24.6) | 376 | 1.1 (1.0-1.2) | -0.4 (-8.0-7.8) | 475 | 1.4 (1.2-1.5) | 0.2 (-8.0-9.0) |
| American Indians and Alaska Natives | 104 | 0.2 (0.1-0.5) | ~ (~-~)$ | 25 | 1.1 (0.7-1.7) | -0.1 (-25.4-33.9) | 30 | 1.3 (0.9-1.9) | 1.9 (-19.3-28.6) |
| Hispanics | 5 | 0.2 (0.1-0.2) | 7.7 (-22.2-48.9) | 495 | 0.9 (0.8-1.0) | 6.1 (-16.0-34.1) | 599 | 1.1 (1.0-1.2) | 6.2 (-16.5-35.1) |
| Sub-Total | 558 | 0.2 (0.1-0.2) | 7.7* (-7.2-25.1) | 3,697 | 1.0 (1.0-1.1) | 4.9 (-6.5-17.7) | 4,255 | 1.2 (1.2-1.2) | 5.3 (-6.4-18.5) |
*
P<0.05, indicating the incidence rate other ethnic groups is significantly different than the rate for Non-Hispanic White;
**
P<0.01, indicating the incidence rate other ethnic groups is significantly different than the rate for Non-Hispanic White;
***
P<0.001, indicating the incidence rate other ethnic groups is significantly different than the rate for Non-Hispanic White.
$
APC was not obtainable from the SEER*Stat.