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. 2023 Feb 27;57:101854. doi: 10.1016/j.eclinm.2023.101854

Table 2.

ePRO Scores over 6 cycles of induction treatment regimen.

ePRO EORTC Domains (0–100) Overall cohorts (A + B)
Cohort A (age <65 years)
Cohort B (age ≥65 years)
Mean baseline scores (SD) Trend (95% CI) (score/cycle) Net average change (95% CI) (score after 6 cycles) p-value Mean baseline scores (SD) Trend (95% CI) (score/cycle) Net average change (95% CI) (score after 6 cycles) p-value Mean baseline scores (SD) Trend (95% CI) (score/cycle) Net average change (95% CI) (score after 6 cycles) p-value
QLQ30 Physical function 78 (23) +2.1 (1.2–3.0) +12.6 (7.2–18) p < 0.0001 85 (20) +1.9 (0.7–3.9) +11.4 (4.2–18.6) p = 0.0032 72 (24) +2.4 (1.1–3.7) +14.4 (6.4–22.4) p = 0.0032
QLQ30 Global health status/QoL 66 (24) +1.7 (0.3–3.1) +10.2 (1.9–18.6) p = 0.016 79 (20) +0.5 (−1.2 to 2.2) +3.0 (−7.2 to 13.2) p = 0.59 56 (22) +3.0 (0.8–5.1) +18 (4.8–30.6) p = 0.0071
MY20 Disease burden symptoms 27 (20) −1.6 (−2.6 to −0.6) −9.6 (−3.8 to −15.4) p = 0.0013 23 (11) −1.4 (−2.6 to −0.2) −8.4 (−15.6 to −1.2) p = 0.02 30 (24) −1.7 (−3.2 to −0.2) −10.2 (−19.2 to −1.2) p = 0.03
MY20 Future perspective 48 (23) −2.8 (−3.8 to −1.8) −16.8 (−23.0 to −10.6) p < 0.0001 48 (25) −3.4 (−4.8 to −2.1) −20.4 (−28.5 to −12.3) p < 0.0001 49 (23) −2.1 (−3.7 to −0.6) −12.8 (−22.1 to −3.6) p = 0.0066
MY20 Self-Body image 20 (24) −0.6 (−2.3 to 1.1) −3.6 (−13.8 to 6.7) p = 0.5 15 (22) −1.3 (−3.5 to 0.9) −7.8 (−21 to 5.4) p = 0.22 23 (26) 0.1 (−2.5 to 2.8) +0.6 (−15 to 16.8) p = 0.91