Representative oxygen generators via self-decomposition for achieving oxygen self-sufficiency. (A) CaO2/B1/NH4HCO3 lipo absorbed NIR to decompose NH4HCO3 to produce CO2 under irradiation, which further induced O2 release from CaO2 NPs and enhanced 1O2 generation. Reproduced from [109] with permission from Royal Society of Chemistry. (B) PolyPPM absorbed long-wavelength light and converted it into short-wavelength light, which promoted the rapid decomposition of Pt (IV) to release O2 and Pt (II). O2 could further generate ROS, while Pt (II) could be used for chemotherapy to realize synergistic PDT chemotherapy, and significantly enhanced the anti-cancer efficacy. Reproduced from [110] with permission from The Author(s). (C) UCPP produced ROS in an O2-independent manner through light response, and generated Pt (II) for chemotherapy, showing excellent chemo-photodynamic therapy efficacy. Reproduced from [111] with permission from Royal Society of Chemistry.