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. 2022 Dec 19;66(3):110–124. doi: 10.3345/cep.2022.00367

Table 2.

Radiological assessment tools for liver fibrosis

Modality Mechanism Advantage Disadvantage
Vibration-controlled transient elastography Vibration induced shear waves Quick bedside assessment
Pediatric probe available
Studied across wide range of liver diseases in children and adults
No real-time USG guidance
Poor performance in congestion, obesity, inflammation [167,168]
2-Dimensional-shear wave elastography Acoustic radiation force impulse creates shear waves Implemented in US scanner
Visualization of liver parenchyma
Less limited by movement
Measures multiple levels simultaneously with color-coding of stiffness values
May be affected by steatosis/inflammation [111]
Age dependent increase [169]
Cutoff values vendor/technique-specific [170]
Effect of body mass index unclear [111,171]
Point shear wave elasto-graphy Acoustic radiation force impulse creates shear waves Implemented in US scanner
Visualization of liver parenchyma
Measures one region of interest
May be affected by steatosis/inflammation [111]
Cutoff values vendor/technique-specific [116]
Magnetic resonance (MR) elastography Acoustic waves delivered by driver placed on patient MR scanner is the probe
Additional cross-sectional imaging
Not limited by anatomic factors
Higher cost
Longer duration
May be affected by steatosis [120]
Breath-holding necessary

USG, ultrasonography; US, ultrasound.