Table 1.
Susceptibility testing of the K. pneumoniae isolates
K. pneumoniae, blood culture, admission | K. pneumoniae, blood culture, hospital day 32 | |||
---|---|---|---|---|
MIC (mg/L) | interpretation | MIC (mg/L) | interpretation | |
VITEK®2 GN74 | ||||
amikacin | ≥64 | R | ≥64 | R |
ampicillin/sulbactam | ≥32/16 | R | ≥32/16 | R |
aztreonam | ≥64 | R | ≥64 | R |
cefazolin | ≥64 | R | ≥64 | R |
cefepime | ≥64 | R | ≥64 | R |
cefoxitin | ≥64 | R | ≥64 | R |
ceftazidime | ≥64 | R | ≥64 | R |
ceftriaxone | ≥64 | R | ≥64 | R |
gentamicin | ≥16 | R | ≥16 | R |
levofloxacin | ≥8 | R | ≥8 | R |
meropenem | ≥16 | R | ≥16 | R |
piperacillin/tazobactam | ≥128/4 | R | ≥128/4 | R |
tobramycin | ≥16 | R | ≥16 | R |
trimethoprim/sulfamethoxazole | ≥16/304 | R | ≥16/304 | R |
Gradient diffusion | ||||
ceftazidime/avibactam | ≥256 | R | ≥256 | R |
ceftolozane/tazobactam | ≥256 | R | ≥256 | R |
meropenem/vaborbactam | ≥256 | R | 24a | R |
tigecyclineb | 1.5 | S | 4 | I |
Disc diffusion | ||||
cefiderocol | 18 mm | S | ||
PAP testing | ||||
cefiderocol | ≥32 | HR | ≥32 | HR |
aztreonam | ≥64 | R | ≥64 | R |
ceftazidime/avibactam | ≥64/4 | R | ≥64/4 | R |
aztreonam/avibactam | 4/4 | S | 4/4 | S |
S, susceptible; I, intermediate; R, resistant; HR, heteroresistant; PAP, population analysis profiling.
Interpretations reported using CLSI breakpoints.
True MIC reported.
Tigecycline is reported using FDA breakpoints.