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. Author manuscript; available in PMC: 2023 Mar 7.
Published in final edited form as: ACS Nano. 2022 Jan 28;16(2):2494–2510. doi: 10.1021/acsnano.1c09108

Figure 8. Organ biodistribution of Cy7-labeled nanoparticles and a free dye control in BALB/c mice.

Figure 8.

(a) Organ biodistribution data not normalized to organ mass, normalized to total radiant efficiency over all organs measured (b). Organ biodistribution data normalized to organ mass, normalized to total radiant efficiency over all organs (c). Blood circulation profiles of nanoparticles, evaluated by measuring blood samples on the IVIS. (d). Retention of NPs at 3h, as a percentage of the amount measured at t = 0. For 8a, 8b, and 8c, n = 3 and for 8d n = 6; for all experiments, ns: p > 0.05; *: p ≤ 0.05; **: p ≤ 0.01; ***: p ≤ 0.001 as determined through 2-way ANOVA with Bonferroni post-tests.