TABLE 1.
Occurrence of repeat types in S. cerevisiae telomere sequences
| TLC1 allele | Total nt evaluated (avg telomere length ± SD) | Total no. of telomeric repeats identified (repeat length in nt) | % Frequency (absolute no.) of repeat type:
|
|||||
|---|---|---|---|---|---|---|---|---|
| TGGGTGTGGT | TGGG(TG)nT | TGGTGGGT | GGGG | TGG (TG)n TGGT | Other | |||
| Genome sequence | 2,407 (NAa) | 215 (11.2) | 49 (105) | 35 (75) | 1 (3) | 1 (2) | 12 (26) | 2 (4) |
| WT | 727 (222 ± 38) | 68 (10.7) | 51 (35) | 41 (28) | 1 (1) | 0 | 4 (3) | 1 (1) |
| WT ΔNcoI | 1,333 (244 ± 26) | 121 (11.0) | 58 (70) | 32 (39) | 2 (2) | 0 | 5 (6) | 3 (4) |
| 473CAC471→ACA | 160 (268 ± 13) | 14 (11.4) | 0 (0)b | 100 (14)c | 0 | 0 | 0 | 0 |
| 484ACA482→CAC + 473CAC471→ACA | 291 (208 ± 28) | 30 (9.7) | 13 (4)b | 83 (25)c | 0 | 0 | 0 | 3 (1) |
| 484ACA482→UUU | 1,371 (247 ± 60) | 125 (11.0) | 51 (64) | 33 (41) | 1 (1) | 2 (2) | 10 (12) | 4 (5) |
| 483CAC481→UUU | 511 (175 ± 13) | 48 (10.6) | 31 (15) | 44 (21) | 0 | 2 (1) | 21 (10) | 3 (1) |
| 484ACA482→CAC | 323 (261 ± 81) | 34 (9.5) | 56 (19) | 41 (14) | 0 | 3 (1) | 0 | 0 |
| 469A→U | 884 (212 ± 35) | 85 (10.4) | 35 (30)d | 63 (54) | 0 | 0 | 0 | 2 (1) |
| 469A→U + 482A→U | 532 (242 ± 39) | 73 (7.3) | 18 (13) | 81 (59) | 0 | 0 | 0 | 1 (1) |
a
NA, not applicable.
b
Sequence GGGTT(GT)nGGT.
c
Sequence GGGTT(GT)n.
d
Contains also GGGTGTGGA sequences.