. Author manuscript; available in PMC: 2023 Mar 7.

Published in final edited form as: Neuropsychopharmacology. 2009 Mar 18;34(7):1819–1828. doi: 10.1038/npp.2009.4

Table 4.

Single SNP associations with decreased orgasm (p<0.05) among 1473 individuals with MDD treated with citalopram for up to 14 weeks

SNP	Minor	Major	Freq (affected)	Freq (unaffected)	Unadjusted				Adjusted (baseline)		Adjusted (ancestry)		Emergent symptoms
SNP	Minor	Major	Freq (affected)	Freq (unaffected)	χ ²	p	OR	95% CI	p	OR	p	OR	p (sex heterogeneity)	p	OR
rs10515697	T	A	0.31	0.26	8.189	0.0042	1.28	1.08, 1.51	0.0123	1.26	0.0139	1.25	0.4813	0.0005	1.49
rs1994862	C	G	0.31	0.26	8.104	0.0044	1.27	1.08, 1.51	0.0132	1.25	0.0146	1.24	0.4968	0.0006	1.48
rs1864205	G	A	0.36	0.32	5.636	0.0176	1.21	1.03, 1.42	0.0836	1.16	0.0628	1.16	0.9275	0.0391	1.26

Column headings refer to unadjusted association, association adjusted for baseline clinical features, association adjusted for ancestry-informative markers, test for heterogeneity between men and women, and association with only confirmed emergent symptoms (ie those not present at initial follow-up visit).