Figure 5.

Identifying potential DmiRNA as regulators of mRNA stability in fibroblasts. miRNA fold-change (FC) for differential miRNAs (DmiRNAs; top row) in C9-ALS fibroblast. Predicted target mRNA (first column) stability values (mature/nascent; second column) are from our previously published study (21). Values in other table cells are the significant Pearson correlation coefficients between each pair of DmiRNA and its predicted mRNA targets; color represents the degree of differential expression in fold-changes (red up-regulation in ALS, blue down-regulation in ALS). Stability-FC and miRNA-FC were scaled independently.