Figure 3.
(A) Representative lumen diameter tracings of an isolated and pressurized posterior cerebral artery (PCA) at 75 mmHg intravascular pressure with ~30% tone, cortical parenchymal arteriole (PA) at 40 mmHg with ~40 % tone and hippocampal arteriole (HA) at 40 mmHg intravascular pressure with ~ 40% tone from male Wistar rats before and after treatment with the nitric oxide synthase (NOS) inhibitor NG-nitro-L-arginine methyl ester (L-NAME, 10−3M). (B) Percent constriction to NOS inhibition. **p<0.01 vs. PCA and PA by one-way ANOVA with post-hoc Bonferroni test.