Table 2. Serum BDNF levels (pg/mL) measured at different time-points by intervention groups.

Time-point	Esketamine (n = 26)	Ketamine (n = 27)	Mean difference (95%CI)	p-value
Baseline*	22,092 (5,880)	21,180 (7,354)	912 (-2,768; 4,593)	0.621
24 hours*	21,871 (6,042)	20,103 (5,685)	1,769 (-1,499; 5,036)	0.282
7 days*	23,292 (4,431)	20,600 (6,157)	2,691 (-409; 5,792)	0.087

BDNF = brain-derived neurotrophic factor; 95%CI = 95% confidence interval.

* Data are expressed as mean (standard deviation).