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. 2022 Apr 20;38(11):3116–3117. doi: 10.1093/bioinformatics/btac272

Fig. 1.

Fig. 1.

Overview of STAAR WDL workflow. The workflow consists of three sequential tasks. A null model is first fit then passed to the testing task, which performs genetic region or gene-centric RV tests in a parallelized approach (genome-wide or for candidate variant sets). The results of the tests are then aggregated in the final task and output to the user