Table 1:
The Environmental Determinants of Diabetes in the Young (TEDDY) Hazard Ratios for Celiac Disease Autoimmunity and Celiac Disease
| Site | Celiac Disease Autoimmunity | Celiac Disease | ||
|---|---|---|---|---|
| Hazard Ratio (95% CI) | P-value | Hazard Ratio (95% CI) | P-value | |
| Washington b | 1.0 | 1.0 | ||
| Georgia | 1.3(1.0–1.6) | 0.05 | 1.4(0.92–2.3) | 0.11 |
| Colorado | 1.3(1.0–1.6) | 0.02 | 2.5(1.7–3.5) | <0.001 |
| Finland | 1.4(1.2–1.8) | <0.001 | 1.9(1.3–2.8) | <0.001 |
| Germany | 1.3(0.99–1.7) | 0.06 | 1.6(0.93–2.6) | 0.09 |
| Sweden | 1.5(1.3–1.9) | <0.001 | 2.8(2.0–3.9) | <0.001 |
a
Model adjusted for HLA haplogenotype, sex, and family history of CD
b
Washington was selected as the reference site as it had the lowest incidence of celiac disease autoimmunity and celiac disease.