Table 3:
Variable | Univariable analyses | Multivariable analysis | ||||
---|---|---|---|---|---|---|
Odds ratio | 95% CI | p-value | Odds ratio | 95% CI | p-value | |
Prophylaxisa | 0.23 | 0.06–0.87 | .030 | 0.18 | 0.05–0.70 | .013 |
GVHD requiring current immunosuppression | 7.96 | 1.70–37.20 | .008 | 11.09 | 2.09–58.75 | .005 |
Prednisone dose ≥20 mg/day | 3.68 | 1.23–11.01 | .020 | |||
Lymphopeniab | 10.7 | 2.17–52.75 | .004 | |||
Retransplant | 1.42 | 0.33–6.07 | .637 | |||
Reduced intensity conditioning | 1.97 | 0.54–7.21 | .308 | |||
Recent CMV infectionc | 4.00 | 1.00–15.99 | .049 | |||
Recent invasive fungal infectionc | 12.00 | 1.25–115.36 | .031 | |||
Morphologic remission | 0.39 | 0.10–1.49 | .168 |
Bold values indicate p <0.05
Abbreviations: CI, confidence interval; CMV, cytomegalovirus; GVHD, graft-versus-host disease.
Includes current use of trimethoprim-sulfamethoxazole and/or doxycycline.
Lymphocyte count <0.5 x109/L.
Within 6 months before the index date.