Table 4.

Multivariable Models for Symptom Outcomes

Outcome	Number of symptoms^a R² = .30		Symptom severity index^b R² = .38		Depressive symptoms^c R² = .47		Anxiety^d R² = .32
Predictor	Coefficient (SE)	p	Coefficient (SE)	p	Coefficient (SE)	p	Coefficient (SE)	p
Age	−0.06 (0.02)	<. 01	−0.32 (0.10)	<.01	−0.11 (0.04)	.01	−0.08 (0.04)	.04
Number of comorbid conditions	0.56 (0.07)	< .01	3.68 (0.45)	<.01	0.83 (0.20)	<.01	0.23 (0.20)	.25
Social isolation	0.11 (0.02)	< .01	0.79 (0.12)	<.01	0.72 (0.05)	<.01	0.55 (0.05)	<.01
Race/Ethnicity
Hispanic	0.17 (0.43)	.69	5.41 (2.70)	.04	1.53 (1.17)	.19	0.23 (1.20)	.85
Non-Hispanic other races	0.77 (0.60)	.20	9.46 (3.79)	<.01	0.00 (1.63)	.99	−0.73 (1.66)	.67
Non-Hispanic White	Ref.		Ref.		Ref.		Ref.
Income meets needs
Meets	−0.31 (0.64)	.63	−11.52 (4.04)	< .01	−2.91 (1.76)	.10	0.17 (1.80)	.92
Barely	−0.09 (0.64)	.88	−6.25 (3.77)	< .01	−1.38 (1.64)	.40	1.43 (1.69)	.40
Not all	Ref.	-	Ref.	-	Ref.	-	Ref.	-
Level of education
More than high school	−0.59 (0.40)	.14	−2.23 (2.48)	.37	−0.85 (1.08)	.43	−0.25 (1.10)	.82
High school or less	Ref.		Ref.		Ref.		Ref.
Marital status
Not married	−0.25 (0.36)	.49	1.47 (2.28)	.52	0.87 (0.99)	.38	−0.70 (1.01)	.49
Married	Ref.		Ref.		Ref.		Ref.
Population of residence
<100,000 people	−0.83 (0.39)	.04	−3.79 (2.47)	.13	−3.10 (1.07)	< .01	−2.70 (1.11)	.02
100,000 or more	Ref.		Ref.		Ref.		Ref.
Cancer and treatment
Female breast chemotherapy/other targeted therapy			5.81 (3.05)	.06	0.83 (1.32)	.53	0.11 (1.36)	.93
Female colorectal/GI	0.27 (0.70)	.69	6.20 (4.38)	.16	−0.46 (1.91)	.81	−0.85 (1.96)	.66
Male colorectal/GI	2.72 (0.80)	< .01	13.96 (5.06)	< .01	0.72 (2.20)	.74	−0.89 (2.25)	.69
Female other	0.45 (0.54)	.40	9.83 (3.36)	< .01	1.40 (1.46)	.34	−0.81 (1.49)	.58
Male other	1.22 (0.58)	.03	10.36 (3.61)	< .01	0.61 (1.56)	.70	−2.02 (1.60)	.21
Female breast hormonal therapy	Ref.		Ref.	-	Ref.		Ref.
Metastatic cancer
Yes	0.45 (0.34)	.19	2.14 (2.15)	.32	1.34 (0.94)	.15	0.96 (0.49)	.63
No	Ref.		Ref.		Ref.		Ref.

Note.

Number of symptoms-potential range 0–17, includes depression and anxiety, higher score = more symptoms;

Summed symptom severity-potential range 0–150, without depression and anxiety, higher score = greater severity;

Center for Epidemiological-Depression scale (CES-D)-potential range 0–60, higher score = worse depression;

Anxiety Patient Reported Outcomes Measurement Information System (PROMIS)-T scores range 43.2–83.1, higher score = more anxiety