TABLE 4.

Results of heterogeneity by the Cochran’s Q test (based on the IVs screened under the genome-wide significance threshold).

Exposure	Outcome	Method	Cochran’s Q test
			Q	Q_df	Q_pval
GERD	Anxiety disorders	Inverse variance weighted	6.345	14	0.957
		MR-Egger	6.345	13	0.933
GERD	Depression	Inverse variance weighted	6.988	15	0.958
		MR-Egger	3.613	14	0.997

GERD, gastroesophageal reflux disease.