TABLE 7.

Results of heterogeneity by the Cochran’s Q test (based on the IVs screened under the locus-wide significance threshold).

Exposure	Outcome	Method	Cochran’s Q test
			Q	Q_df	Q_pval
GERD	Anxiety disorders	Inverse variance weighted	47.140	74	0.994
		MR-Egger	46.788	73	0.993
GERD	Depression	Inverse variance weighted	52.773	78	0.987
		MR-Egger	50.320	77	0.992

GERD, gastroesophageal reflux disease.