Table 1.
MR analyses showing the associations of genetically Inflammatory markers with the Risk of ISSHL.
| MR approaches | SNPs | OR | (95% CI) | P-value |
|---|---|---|---|---|
| CRP | ||||
| IVW | 53 | 1.45 | (1.05, 1.98) | 0.03 |
| Weighted median | 53 | 1.23 | (1.02, 1.49) | 0.02 |
| MR-Egger | 53 | 1.10 | (0.83, 1.46) | 0.49 |
| MR-PRESSO | 53 | / | / | 0.36 |
| TNF-α | ||||
| IVW | 5 | 1.14 | (0.88, 1.49) | 0.30 |
| Weighted median | 5 | 1.19 | (0.85, 1.66) | 0.30 |
| MR-Egger | 5 | 1.07 | (0.68, 1.70) | 0.78 |
| MR-PRESSO | 5 | / | / | 0.52 |
| Fibrinogen | ||||
| IVW | 18 | 1.04 | (0.88, 1.25) | 0.59 |
| Weighted median | 18 | 1.60 | (0.85, 1.31) | 0.60 |
| MR-Egger | 18 | 1.40 | (0.97, 2.04) | 0.09 |
| MR-PRESSO | 18 | / | / | 0.11 |