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. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: Alcohol Clin Exp Res (Hoboken). 2022 Dec 16;47(2):336–347. doi: 10.1111/acer.14988

Figure 1. Affective and nociceptive phenotypes associated with withdrawal from moderate and excessive alcohol drinking in C57BL/6J females raised under control (CTL) or limited bedding and nesting (LBN) conditions (Experiment 1).

Figure 1.

A. Experimental timeline (EPM, elevated plus-maze; TST, tail suspension test; TPT, tail pressure test). B-C. EPM: % time spent on open arms (B) and total distance traveled (C). D. Digging test: digging duration. ####, main effect of CIE, p<0.0001. E. Splash test: number of grooming bouts. #, main effect of CIE, p<0.05. F. TST: immobility duration. ##, main effect of CIE, p<0.01. G. TPT: nociceptive threshold. **, main effect of LBN, p<0.01.