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. 2023 Mar 7;6:245. doi: 10.1038/s42003-023-04615-6

Fig. 4. Mre-11 dependent overexpression of CD47 in response to γ-irradiation.

Fig. 4

a HEK-293T cells were treated either with Nu7026 (10 µM), Ku55933 (10 µM), or mirin (100 µM) and then exposed to γ-irradiation. Graphs depict CD47 expression (MFI) in HEK-293T cells at 24 h after irradiation. b Depletion of mre-11 by shRNA in 293T cells (right panel) abrogated CD47 upregulation upon γ-irradiation (left graph). c CD47 expression on HF, BJ-5a and ATLD2 cells in response to γ-irradiation. Graph shows an average (± STD) of four replicates in each group. Representative of three independent experiments is shown. ns: non-significant; **p < 0.005; ****p < 0.0001.