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. 2023 Feb 22;14:1119046. doi: 10.3389/fphar.2023.1119046

FIGURE 4.

FIGURE 4

Effect of meldonium on pharmacodynamic blood tests under acute hypoxia injury. (A) Routine blood examination; (B) Biochemical analyses. Data are presented as the mean ± SEM (n = ). # p < 0.05, ## p < 0.01 and ### p < 0.001 compared to the normoxia group; * p < 0.05 and ** p < 0.01 compared to the high-altitude hypoxia with saline group. The data were analyzed using one-way ANOVA analysis of variance with Tukey’s post-tests. H-25, H-50, H-100, H-200, H-400, indicate different doses of meldonium under hypoxia, respectively, and H-ACZ indicates the administration of acetazolamide under hypoxia.