Table 2.
Probiotics in the treatment of various cancers and gastro-intestinal diseases
| Name of gastrointestinal disease | Symptoms of the disease | Strain of probiotic recommended | Amount of Probiotic administered | Disease Cured in | References |
|---|---|---|---|---|---|
| Acute infectious diarrhea | Changes in bowel movement, increase in the water content, and frequency of stools | Saccharomyces boulardii | 250 and 750 mg | ~ 24 h-73 h | (Dinleyici et al., 2015) |
| Ulcerative Colitis | Diffuse mucosal inflammation, bloody diarrhoea, and abdominal pain | E. coli and Lactobacillus GG | 100 mg to 200 mg per day | 6 months | (Kaur et al., 2020) |
| Antibiotic-Associated Diarrhea | Severity to result in colitis, electrolyte disturbance, and bowel perforation | L. acidophilus, L. casei | 5 × 109 viable bacteria | 4 weeks | (Goldenberg et al., 2017b) |
| Crohn’s Disease | Fever, fatigue, Blood in your stool, and mouth sores | Bifidobacterium longum | 2 × 1011 freeze-dried viable | 6 months | (O’Callaghan and van Sinderen, 2016b) |
| Traveller’s Diarrhea | An urgent need to defecate, Nausea, Vomiting | Lacticaseibacillus rhamnosus | 2 × 109 CFU | 1 week | (Giddings et al., 2016) |
| C. difficile diarrhea | Waterydiarrhea, Rapid heart rate, nausea Lossof appetite, Weight loss | S. boulardii | 1000 mg per day | 4 weeks | (Moré and Swidsinski, 2015) |
| Irritable Bowel Syndrome | Discomfort or pain associated with an alteration in bowel habits constipation | Propionibacterium freudenreichiis sp shermanii | 1 × 107 CFU | 23 weeks | (Didari, 2015) |
| C. albicans-associated gut discomfort | Abdominal or pelvic pain, Blood in your urine | L. rhamnosus; B. animalis subsp. lactis | 1 × 109 CFU | 14 weeks | (Severance et al., 2017) |
| Colorectal cancer | persistent change in bowel habits, Rectal bleeding | Lactobacillus and Bifidobacterial | 30 × 107 CFU | 6 months | (Zaharuddin et al., 2019) |
| Head and neck Squamous Cell Carcinoma | A persistent sore throat, and pain or difficulty swallowing | Bifidobacterium breve lw01 | 1 × 109 CFU | 3 weeks | (Johnson et al., 2020) |
| Severe acute pancreatitis | Fever, Higher heart rate, Swollen and tender belly | L. plantarum | 3 × 107 cfu | 2 weeks | (Oláh and Jr, 2014) |